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Osteoporosis Circumscripta on 68Ga-DOTATATE PET CT

Gandy, Nemi, MBBS, FRCR; Ordidge, Katherine Louise, MBBS, FRCR, PhD; Arshad, Mubarik, MBBS, MRCP, FRCR; Win, Zarni, MBBS, MRCP, FRCR

doi: 10.1097/RLU.0000000000002567
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Incidental findings on PET CT studies are common. The distribution of 68Ga-DOTATATE is dependent on cell surface expression of somatostatin receptors, which may be pathologic or physiologic. Osteoporosis circumscripta is the early lytic phase of Paget disease associated with well-defined osteopenia, most commonly seen within the skull on imaging. The appearance has been well demonstrated on 99mTc HDP/MDP bone scans. Here, we present the case of a 76-year-old man with a small bowel carcinoid tumor who underwent staging imaging with 68Ga-DOTATATE PET CT with the incidental finding of osteoporosis circumscripta.

From the Nuclear Medicine Department, Imperial College Healthcare NHS Trust, Charing Cross Hospital, Fulham Palace Road, London, United Kingdom.

Received for publication November 15, 2018; revision accepted February 17, 2019.

Conflicts of Interest and sources of funding: none declared.

Correspondence to: Nemi Gandy, MBChB, Imperial College Healthcare NHS Trust London, London, United Kingdom. E-mail:

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