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Gated Tomographic Radionuclide Angiography Using CZT Gamma Camera in Patients Receiving Cardiotoxic Chemotherapy

Going Faster and Less Irradiating

Bailly, Matthieu, MD*; Le Rouzic, Gilles; Metrard, Gilles, MD*

doi: 10.1097/RLU.0000000000002569
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Tomographic radionuclide angiography (TRNA) can monitor cardiac function in patients receiving cardiotoxic chemotherapy. Gamma cameras using CZT detectors enable dose reduction and quicker acquisitions. We report 80 patients who underwent a 7-minute TRNA acquisition after injection of 550-MBq 99mTc–labeled human serum albumin. Data were analyzed full and half. Image quality was not visually decreased. There was no significant difference in left ventricular systolic and diastolic volumes and in left and right ventricular ejection fractions between full and half data acquisitions (P < 0.0001). When injecting half activity, effective dose could be reduced to 1.92 mSv.

From the *Nuclear Medicine Department, and

Radioprotection Department, CHR Orleans, Orleans, France.

Received for publication December 9, 2018; revision accepted February 18, 2019.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Matthieu Bailly, MD, Service de médecine nucléaire, CHR Orleans, 14 Avenue de l'Hopital, 45100 Orleans, France. E-mail: matthieu.bailly@chr-orleans.fr.

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