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FDG PET in Diffuse Spinal Carcinomatous Meningitis

Cuvilliers, Cécile, MD*; Ahrweiller, Flora, MD; Vauléon, Elodie, MD, PhD; Castelli, Joël, MD, PhD†§; Palard-Novello, Xavier, MD, PhD

doi: 10.1097/RLU.0000000000002555
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A 65-year-old man, diagnosed with right paranasal sinus neuroendocrine carcinoma with skull base invasion and ipsilateral lymph node involvement underwent chemotherapy. Six months later, the patient underwent radiation therapy for right cervical lymph node recurrence. Two months after the end of the radiation therapy, the patient was referred to our department to perform a whole-body FDG PET for therapeutic assessment. It showed diffuse intense FDG uptake of the whole spinal canal. The physical examination revealed walking disorders. Meningeal contrast enhancement on MRI of the brain and the spinal cord was leading to the diagnosis of carcinomatous meningitis.

From the Departments of *Nuclear Medicine,

Radiation Oncology, and

Medical Oncology, Centre Eugène Marquis; and

§Univ Rennes, Inserm, LTSI-UMR1099, Rennes, France.

Received for publication January 9, 2019; revision accepted February 7, 2019.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Xavier Palard-Novello, MD, PhD, Department of Nuclear Medicine, Centre Eugène Marquis, Avenue de la Bataille Flandres-Dunkerque, 35000, Rennes, France. E-mail:

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