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Asymptomatic Prostate Cancer Brain Metastases on 68Ga-PSMA PET/CT

Yin, Charlotte, MBBS; Ho, Bao, MBBS, FRANZCR; Chan, Lyn, MBBS, FRACP; Emmett, Louise, MbChB, MD, FRACP

doi: 10.1097/RLU.0000000000002548
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Brain metastases from prostate cancer are rare and occur at a late stage in the natural history of the disease. Men usually present with neurological manifestations. We present a 66-year-old asymptomatic man who had incidental brain metastases detected on 68Ga-PSMA PET/CT, which was later confirmed on biopsy to be prostate adenocarcinoma. With newer androgen deprivation agents and improved imaging capabilities increasing the mean survival and thus the incidence of brain metastases from prostate cancer, it is important to consider this important differential not only in men who display neurological symptoms but also in men who are asymptomatic.

From St Vincent's Hospital, Darlinghurst, New South Wales, Australia.

Received for publication May 23, 2018; revision accepted February 6, 2019.

Conflicts of interest and sources of funding: none declared.

The patient had provided informed consent to the publication of his deidentified PET and MRI scans. No ethics approval through an institutional committee on human research was required.

Correspondence to: Charlotte Yin, MBBS, St Vincent's Hospital, 390 Victoria St, Darlinghurst, New South Wales, 2010, Australia. E-mail:

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