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Aberrant Hypermetabolism of Benign Uterine Leiomyoma on 18F-FDG PET/CT

Nunes, Rafael F., MD*; Queiroz, Marcelo A., MD*; Buchpiguel, Carlos Alberto, MD, PhD*; Carvalho, Filomena Marino, MD, PhD; Carvalho, Jesus Paula, MD, PhD

doi: 10.1097/RLU.0000000000002580
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Leiomyomas are prevalent benign smooth muscle tumors in the uterus, displaying variable degrees of FDG uptake on PET/CT. The glucose metabolism intensity of those lesions relies on biologic features and markedly increased FDG accumulation is more typically related to malignant diseases, as in the case of leiomyosarcomas. Notwithstanding that uterine fibroids typically exhibit mild to moderate FDG uptake, in this article we report a case of unexpectedly intense hypermetabolism of a benign uterine leiomyoma on a PET/CT scan performed for initial staging of a breast cancer patient.

From the *PET/CT and Nuclear Medicine Department, Imaging Division;

Department of Pathology and

Department of Gynecologic Oncology—Hospital Sírio-Libanês, São Paulo, Brazil.

Received for publication December 14, 2018; revision accepted February 24, 2019.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Rafael Fernandes Nunes, MD, PET/CT and Nuclear Medicine Department, Imaging Division—Hospital Sírio-Libanês, Rua Dona Adma Jafet 91, São Paulo 01308-050, Brazil. E-mail:

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