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68Ga-PSMA Uptake in Fibrous Dysplasia

Reale, Maria Lucia, MD*; Buttigliero, Consuelo, MD*; Tucci, Marcello, MD*; Giardino, Roberto, MD; Poti, Carlo, MD

doi: 10.1097/RLU.0000000000002546
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Prostate cancer is one of the most common malignancies. Imaging tools play an important role throughout the entire process of the disease. The scenario, however, is going to change. Thanks to a higher sensitivity and specificity, the use of the prostate-specific membrane antigen (PSMA) PET is of increasing importance, particularly at the time of diagnosis and in case of biochemical recurrence. Nevertheless, previous reports have described false-positive findings, as tracer-avid physiological findings or benign processes, potential pitfalls for interpretation of 68Ga-PSMA PET/CT. Here we report a case of PSMA uptake in a histologically proven fibrous dysplasia.

From the *Division of Medical Oncology, and

Department of Thoracic Surgery, University of Turin, San Luigi Gonzaga Hospital, Orbassano, Turin; and

Unit of Nuclear Medicine, Aosta Regional Hospital, Aosta, Italy.

Received for publication October 29, 2018; revision accepted February 5, 2019.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Maria Lucia Reale, MD, Division of Medical Oncology, Ospedale San Luigi Gonzaga, Regione Gonzole 10–10043 Orbassano, Turin, Italy. E-mail:

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