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68Ga DOTATATE PET/CT Versus 18F-FDG PET/CT for Detecting Intramedullary Hemangioblastoma in a Patient With Von Hippel-Lindau Disease

Banezhad, Farnaz, MD*; Kiamanesh, Zahra, MD*; Emami, Farshad, MD; Sadeghi, Ramin, MD*

doi: 10.1097/RLU.0000000000002565
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Von Hippel-Lindau disease is an inherited syndrome associated with several benign and malignant tumors such as central nervous system (CNS) hemangioblastoma. Herein, we report a known case of A Von Hippel-Lindau patient with a cerebral hemangioblastoma who was referred for further evaluation because of recent paraparesis. 18F-FDG PET/CT showed no focal uptake in the thoracic spine, which demonstrated increased 68Ga DOTATATE activity, owing to overexpression of somatostatin receptors, suggesting spinal cord hemangioblastoma. This case report indicates the significant role of 68Ga-labeled somatostatin receptor analogs in the diagnosis of hemangioblastoma.

From the *Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad; and

Nuclear Medicine & Molecular Imaging Department, Imam Reza International University, Mashhad, Iran.

Conflicts of interest and sources of funding: none declared.

Received for publication August 7, 2018; revision accepted February 18, 2019.

Correspondence to: Ramin Sadeghi, MD, Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. E-mail: sadeghir@mums.ac.ir; raminsadeghi1355@yahoo.com.

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