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Ochronosis Involvement and Extensity With 18F-FDG PET/CT

Acar, Emine, MD*,†; Bekiş, Recep, MD; Zengin, Berin, MD§; Birlik, Merih, MD§

doi: 10.1097/RLU.0000000000002518
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Ochronosis (alkaptonuria) is an autosomal recessive inherited metabolic disease that causes pigmentation by accumulation of homogenous acid in the connective tissue. The most important causes of morbidity are ochronotic arthropathy and cardiovascular involvement seen in fourth and sixth decades, respectively. In this case report, we report the prevalence of 18F-FDG PET/BT findings in a 48-year-old man with ochronosis who underwent 18F-FDG PET/BT imaging for the evaluation of mediastinal lymphadenopathy.

From the *Department of Nuclear Medicine, Izmir Katip Celebi University, Ataturk Training and Research Hospital;

Department of Translational Oncology, Dokuz Eylul University, Graduate School of Health Sciences;

Department of Nuclear Medicine, Dokuz Eylul University, School of Medicine; and

§Department of Internal Medicine, and Division of Rheumatology, Dokuz Eylul University, School of Medicine, Izmir, Turkey.

Received for publication December 7, 2018; revision accepted January 22, 2019.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Emine Acar, MD, İzmir Kâtip Çelebi Üniversitesi Atatürk Eğitim ve Araştirma Hastanesi Nükleer Tip Anabilim Dali Karabağlar/İzmir/Turkey. E-mail:

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