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Superscan 18F-Fluciclovine PET/CT of PSA-Negative Prostate Cancer Bone Metastases

Chen, Bo MD; Macapinlac, Homer A. MD; Lu, Yang MD, PhD

doi: 10.1097/RLU.0000000000002478
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A 76-year-old man presented with recently diagnosed prostate adenocarcinoma, Gleason score of 4 + 4, and a Super bone scan with concurrent PSA of 1.7 ng/mL. Approximately 3.5 months later, an 18F-fluciclovine PET/CT was performed despite of a decreased PSA of 0.3 ng/mL. A Superscan fluciclovine PET/CT was identified, and bone metastasis were later confirmed at biopsy.

From the Department of Nuclear Medicine, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX.

Received for publication December 1, 2018; revision accepted December 18, 2018.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Yang Lu, MD, PhD, Division of Diagnostic Imaging, Department of Nuclear Medicine, The University of Texas MD Anderson Cancer Center, 1400 Pressler St, Unit Number 1483, Houston, TX 77030. E-mail:

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