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Spontaneous Regression of Clinically Indolent Lymphomas Revealed by 18F-FDG PET/CT

Pan, Qingqing MD*†; Luo, Yaping MD*†; Cao, Xinxin MD; Zhang, Yan MD; Li, Fang MD*†

doi: 10.1097/RLU.0000000000002457
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A 48-year-old man and a 55-year-old woman, who were diagnosed with follicular lymphoma and small B lymphocytic cell lymphoma, respectively, underwent initial “watch-and-wait” approach against lymphoma. The initial 18F-FDG PET/CT of both patients showed multiple FDG-avid lymph nodes in the neck, mediastinum, abdomen, and inguinal regions. During their active surveillance, the follow-up PET/CT of both patients revealed spontaneous regression of lymphoma.

From the *Department of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital

Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine

Department of Hematology, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, China.

Received for publication November 2, 2018; revision accepted November 28, 2018.

Conflicts of interest and sources of funding: This work was supported by the National Natural Science Foundation of China (81701741). None declared to all authors.

Correspondence to: Yaping Luo, MD, Wangfujing, Dongcheng District, Beijing 100730, People's Republic China. E-mail:

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