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Spontaneous Regression of Clinically Indolent Lymphomas Revealed by 18F-FDG PET/CT

Pan, Qingqing, MD*†; Luo, Yaping, MD*†; Cao, Xinxin, MD; Zhang, Yan, MD; Li, Fang, MD*†

doi: 10.1097/RLU.0000000000002457
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A 48-year-old man and a 55-year-old woman, who were diagnosed with follicular lymphoma and small B lymphocytic cell lymphoma, respectively, underwent initial “watch-and-wait” approach against lymphoma. The initial 18F-FDG PET/CT of both patients showed multiple FDG-avid lymph nodes in the neck, mediastinum, abdomen, and inguinal regions. During their active surveillance, the follow-up PET/CT of both patients revealed spontaneous regression of lymphoma.

From the *Department of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital;

Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine; and

Department of Hematology, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, China.

Received for publication November 2, 2018; revision accepted November 28, 2018.

Conflicts of interest and sources of funding: This work was supported by the National Natural Science Foundation of China (81701741). None declared to all authors.

Correspondence to: Yaping Luo, MD, Wangfujing, Dongcheng District, Beijing 100730, People's Republic China. E-mail:

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