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High-Resolution Brain 18F-FDG Images Provided by Fully Digital PET

Salvadori, Julien, PhD*†; Perrin, Mathieu, MD; Marie, Pierre-Yves, MD, PhD†‡§; Imbert, Laëtitia, PhD*†‡∥; Verger, Antoine, MD, PhD*†‡

doi: 10.1097/RLU.0000000000002483
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Normal 18F-FDG PET">brain 18F-FDG PET images, consecutively recorded on analog and fully digital PET cameras in an 85-year-old woman, are depicted herein with the reconstruction methods recommended for a 2-mm voxel size on each camera and with a high-resolution reconstruction additionally developed for digital PET with a 1-mm voxel size. An enhanced gray-to-white matter contrast was consistently documented for digital PET when compared with analog PET, and was associated with a further enhancement in spatial resolution at 1-mm voxel size, as evidenced by a much clearer delineation of cortical gyri. These high-resolution images could favor the identification of brain abnormalities.

From the *Université de Lorraine, INSERM, IADI, Nancy;

CHRU-Nancy, Université de Lorraine, Plateforme Nancyclotep,

CHRU-Nancy, Université de Lorraine, Service de Médecine Nucléaire, and

§Université de Lorraine, INSERM, Centre d'Investigations Cliniques Plurithématiques, Nancy, Vandœuvre-lès-Nancy; and

Université de Lorraine, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.

Received for publication September 18, 2018; revision accepted December 25, 2018.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Julien Salvadori, PhD, Service de Médecine Nucléaire, rue du Morvan, 54500 Vandœuvre-lès-Nancy, France. E-mail:

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