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18F-FDG PET/CT in Intramuscular Mantle Cell Lymphoma With Elongated Lymphomatous Neurovascular Extension

Hod, Nir MD, MHA; Levin, Daniel MD; Anconina, Reut MD; Ezroh Kazap, Dina MD; Lantsberg, Sophie MD

doi: 10.1097/RLU.0000000000002466
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Skeletal muscle involvement by lymphoma is rare, particularly for mantle cell lymphoma. We describe a 65-year-old man who presented with a rapidly growing left thigh mass. FDG PET/CT characterized the mass as malignant. Interestingly, an unusual hypermetabolic elongated tumorous extension was demonstrated arising from the intramuscular mass disseminating alongside the neurovascular bundle of the thigh up to the groin. Histopathology revealed intramuscular mantle cell lymphoma. In this case, we aim to highlight this interesting FDG PET/CT imaging finding, which can serve as a clue allowing one to strongly suggest lymphoma as the leading diagnosis.

From the Institute of Nuclear Medicine and Molecular Imaging, Soroka University Medical Center, Affiliated to Ben Gurion University of the Negev, Faculty of Health Sciences, Beer-Sheva, Israel.

Conflicts of interest and sources of funding: none declared.

Received for publication October 2, 2018; revision accepted December 7, 2018.

Correspondence to: Sophie Lantsberg, MD, Institute of Nuclear Medicine and Molecular Imaging, Soroka University Medical Center, POB 151, Beer-Sheva, Israel. E-mail: SophieL@clalit.org.il; and Nir Hod, MD, MHA, Institute of Nuclear Medicine and Molecular Imaging, Soroka University Medical Center, POB 151, Beer-Sheva, Israel. E-mail: hod_n@yahoo.com.

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