11C-acetate PET can quantify myocardial blood flow and oxidative metabolism (kmono) with a single imaging study. We present a 63-year-old man with myocardial infarction with nonobstructive coronary arteries due to vasospasm, who underwent 11C-acetate PET after antispastic medication. By quantifying myocardial blood flow and kmono, 11C-acetate PET could detect the initial ischemic insult by vasospasm and sufficient amount of remaining viable myocardium, while excluding significant inducible ischemia. We suggest that 11C-acetate PET can be a clinically valuable tool for assessing the pathophysiology of myocardial infarction with nonobstructive coronary arteries.
From the Departments of *Nuclear Medicine and
†Cardiology, Chonnam National University Hospital, Gwangju; and
‡Department of Nuclear Medicine, Chonnam National University Hwasun Hospital, Jeonnam, Republic of Korea.
Received for publication October 18, 2018; revision accepted November 7, 2018.
S.-G.C. and Y.K. equally contributed to this work as the co–first authors.
Conflicts of interest and sources of funding: Dr. H.-S.B. receives research fund from the Basic Science Research Program through the National Research Foundation of Korea, funded by the Ministry of Education (NRF-2016R1D1A3B01006631). None declared to all other authors.
Correspondence to: Myung Ho Jeong, MD, PhD, FACC, FAHA, FESC, FSCAI, Department of Cardiology, Chonnam National University Hospital, 42, Jebong-ro, Dong-gu, Gwangju, Republic of Korea 61469. E-mail: email@example.com; and Hee-Seung Bom, MD, PhD, FANMB, Department of Nuclear Medicine, Chonnam National University Hwasun Hospital, 322, Seoyang-ro Hwasun-eup, Hwasun-gun, Jeonnam, Republic of Korea 58128. E-mail: firstname.lastname@example.org.