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Myocardial Infarction With Nonobstructive Coronary Arteries Assessed by 11C-Acetate Cardiac PET

Cho, Sang-Geon, MD, PhD*; Kim, Yongcheol, MD; Jeong, Myung Ho, MD, PhD, FACC, FAHA, FESC, FSCAI; Bom, Hee-Seung, MD, PhD, FANMB

doi: 10.1097/RLU.0000000000002431
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11C-acetate PET can quantify myocardial blood flow and oxidative metabolism (k mono) with a single imaging study. We present a 63-year-old man with myocardial infarction with nonobstructive coronary arteries due to vasospasm, who underwent 11C-acetate PET after antispastic medication. By quantifying myocardial blood flow and k mono, 11C-acetate PET could detect the initial ischemic insult by vasospasm and sufficient amount of remaining viable myocardium, while excluding significant inducible ischemia. We suggest that 11C-acetate PET can be a clinically valuable tool for assessing the pathophysiology of myocardial infarction with nonobstructive coronary arteries.

From the Departments of *Nuclear Medicine and

Cardiology, Chonnam National University Hospital, Gwangju; and

Department of Nuclear Medicine, Chonnam National University Hwasun Hospital, Jeonnam, Republic of Korea.

Received for publication October 18, 2018; revision accepted November 7, 2018.

S.-G.C. and Y.K. equally contributed to this work as the co–first authors.

Conflicts of interest and sources of funding: Dr. H.-S.B. receives research fund from the Basic Science Research Program through the National Research Foundation of Korea, funded by the Ministry of Education (NRF-2016R1D1A3B01006631). None declared to all other authors.

Correspondence to: Myung Ho Jeong, MD, PhD, FACC, FAHA, FESC, FSCAI, Department of Cardiology, Chonnam National University Hospital, 42, Jebong-ro, Dong-gu, Gwangju, Republic of Korea 61469. E-mail: myungho@chollian.net; and Hee-Seung Bom, MD, PhD, FANMB, Department of Nuclear Medicine, Chonnam National University Hwasun Hospital, 322, Seoyang-ro Hwasun-eup, Hwasun-gun, Jeonnam, Republic of Korea 58128. E-mail: hsbom@jnu.ac.kr.

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