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Small Primary Cutaneous γδT-Cell Lymphoma Lesions Successfully Treated With Pralatrexate

Imataki, Osamu, MD; Uchida, Shumpei, MD; Yokokura, Shigeyuki, MD, PhD; Uemura, Makiko, MD; Kadowaki, Norimitsu, MD, PhD

doi: 10.1097/RLU.0000000000002409
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Here we report on the treatment of a 38-year-old woman with primary cutaneous γδT-cell lymphoma, which is a rare subset of cutaneous T-cell lymphoma. She presented with multiple subtle subcutaneous nodules, which were not clearly observed on computed tomography scans or after biopsy. However, 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) accurately detected small cutaneous lesions. She achieved a second complete remission, as demonstrated by 18F-FDG-PET performed after pralatrexate infusion.

From the Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Received for publication April 15, 2018; revision accepted October 23, 2018.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Osamu Imataki, MD, Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Kagawa University, 1750–1 Ikenobe, Miki-town, Kita-county, Kagawa 761–0793, Japan. E-mail: oima@med.kagawa-u.ac.jp.

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