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Large Paraesophageal Schwannoma With Intense Prostate-Specific Membrane Antigen Expression on 68Ga-PSMA-PET/CT Mimicking Lymph Node Metastasis in a Patient With Prostate Cancer

Ries, Martin, MD*; Khreish, Fadi, MD*; Veith, Christian, MD; von den Hoff, Joachim, MD; Ezziddin, Samer, MD*

doi: 10.1097/RLU.0000000000002359
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Prostate-specific membrane antigen (PSMA)-PET/CT as an emerging modality in molecular imaging will lead to earlier detection and localization of relapse in prostate cancer but will undoubtedly also lead to false-positive findings, as it becomes clear that this new tracer is not as specific as its name would suggest. In this context, we present a case of a large PSMA-expressing schwannoma, a rare nerve sheath tumor mimicking paraesophageal lymph node metastasis in a patient with a history of prostate cancer and biochemical recurrence.

From the Departments of *Nuclear Medicine, and

Pathology, Saarland University Hospital, Hamburg; and

Centre of Urology, Wittlich, Germany.

Received for publication August 30, 2018; revision accepted September 25, 2018.

Conflicts of interest and sources of funding: none declared.

Consent to publish: Informed consent was obtained from the individual participant included in the study.

Availability of data and materials: PET/CT datasets are available from the corresponding author on request.

Correspondence to: Martin Ries, MD, Klinik für Nuklearmedizin, Uniklinikum des Saarlandes, Kirrberger St, 66421, Hamburg, Germany. E-mail:

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