Interesting ImagesIncreased 99mTc Pertechnetate Uptake But Unimpressive 131I Activity in the Metastatic Mediastinal Lymph Nodes in a Thyroid Cancer PatientShao, Fuqiang MD∗,†,‡; Zhou, Dan MD‡; Lan, Xiaoli MD, PhD∗,†Author Information From the ∗Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan †Hubei Key Laboratory of Molecular Imaging, Wuhan ‡Department of Nuclear Medicine, Zigong First People’s Hospital, Zigong, China. Received for publication October 12, 2018; revision accepted October 18, 2018. Conflicts of interest and sources of funding: This work was supported by the Key Project of Hubei Province Technical Innovation Special Funding (No. 2017ACA182), and the Clinical Research Physician Program of Tongji Medical College, Huazhong University of Science and Technology (No. 5001530008). None declared to all authors. Correspondence to: Xiaoli Lan, MD, PhD, Department of Nuclear Medicine, Wuhan Union Hospital, No. 1277 Jiefang Ave, Wuhan, 430022, China. E-mail: LXL730724@hotmail.com. Clinical Nuclear Medicine: February 2019 - Volume 44 - Issue 2 - p 176-178 doi: 10.1097/RLU.0000000000002405 Buy Metrics Abstract False negative 131I accumulation in metastatic lesions of thyroid carcinoma could be due to various etiologies. Here we present a 33-year-old woman with a history of papillary thyroid cancer who had increased 99mTc pertechnetate activity in the mediastinal metastatic lymph nodes, which was not clearly seen on whole body 131I scan due to adjacent activity from lung metastases. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.