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Incidental Finding of Intrathyroid Metastases of Prostatic Cancer on 18F-Choline PET/CT

Vija Racaru, Lavinia, PhD, MD*; Gabiache, Erwan, MD*†; Fontaine, Sebastien, MD*‡; D'Aure, Dominique, MD§; Mourey, Loic, MD; Courbon, Frederic, MD, PhD*; Zerdoud, Slimane, MD*

doi: 10.1097/RLU.0000000000002374
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An 85-year-old man with a 2-year history of prostate cancer, treated with radiotherapy and hormonal therapy, presented increased prostatic-specific antigen levels. 18F-choline PET/CT showed focal prostatic uptake consistent with known local recurrence, increased uptake of 2 hypodense thyroid nodules and of 2 left cervical lymph nodes, suspected as thyroid cancer. Neck ultrasound confirmed the high risk of malignancy, and a guided biopsy (of a thyroid nodule and cervical lymph node) revealed cellular infiltrates thyroid transcription factor-1 (TTF-1) negative and prostatic-specific antigen positive, confirming intrathyroid and cervical lymph node metastases of prostate cancer. PET/CT changed the disease staging. Chemotherapy was initiated.

From the *Nuclear Medicine Department, Institut Universitaire de Cancérologie-Oncopole, Institut Claudius Regaud;

Nuclear Medicine Department, Pasteur Clinic;

Endocrinology Department, Joseph Ducuing Hospital;

§Pathology Department, CHU Toulouse; and

Oncology Department, Institut Universitaire de Cancérologie-Oncopole, Institut Claudius Regaud, Toulouse, France.

Received for publication August 9, 2018; revision accepted October 2, 2018.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Lavinia Vija Racaru, MD, PhD, Nuclear Medicine Department, Institut Universitaire de Cancérologie-Oncopole, Institut Claudius Regaud, 1 Av. Irène Joliot-Curie, 31100 Toulouse, France. E-mail: vija_lm@yahoo.com.

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