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Gallbladder Metastasis From Conjunctival Melanoma

Cassou-Mounat, Thibaut, MD; Luporsi, Marie, MD; Huchet, Virginie, MD; Jehanno, Nina, MD

doi: 10.1097/RLU.0000000000002413
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Malignant conjunctival melanoma is a rare tumor. A 46-year-old woman with a history of locally recurrent left conjunctival melanoma was followed by 18F-FDG PET/CT. Four years after the local recurrence treated by orbital exenteration, the follow-up PET/CT scan showed an incidental intense FDG uptake mass infiltrating the gallbladder associated with a low uptake of an infracentimetric pulmonary nodule. The patient was completely asymptomatic with no sign of local recurrence. Laparoscopic cholecystectomy was performed, and histopathologic findings were consistent with gallbladder metastasis of melanoma. After almost 2 years of immunotherapy, the patient is still in complete response.

From the Department of Nuclear Medicine, Institut Curie, PSL Research University, Paris, France.

Received for publication August 29, 2018; revision accepted October 25, 2018.

Conflicts of interest and sources of funding: none declared.

Informed consent: According to French regulations, patients were informed of research performed during their treatment and provided informed consent.

Correspondence to: Thibaut Cassou-Mounat, MD, Department of Nuclear Medicine, Institut Curie, PSL Research University, 26 Rue d'Ulm, 75005 Paris, France. E-mail: thibaut.cassoumounat@curie.fr.

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