Diffuse Large B-Cell Lymphoma Recurring as Neurolymphomatosis on FDG PET/CTGaneshalingam, Rueben, MBBS; Roach, Paul, MBBS, FRACP, FAANMS; Schembri, Geoffrey Paul, MBBS, FRACP, BScClinical Nuclear Medicine: February 2019 - Volume 44 - Issue 2 - p 145–147 doi: 10.1097/RLU.0000000000002388 Interesting Images Buy Abstract Author InformationAuthors Article MetricsMetrics Two patients with diffuse large B-cell lymphoma relapsing as neurolymphomatosis diagnosed on FDG PET/CT are presented. Both patients were treated initially with chemotherapy and had a complete metabolic response. Patient 1 represented with lower-limb pain. An FDG PET/CT demonstrated intense uptake throughout the sciatic nerves bilaterally extending distally with relapse confirmed on biopsy. Patient 2 represented to hospital with worsening mobility, neuropathic pain, and facial asymmetry. An FDG PET/CT demonstrated relapse within the spinal cord, left sciatic nerve, and facial nerve branches. Neurolymphomatosis is an uncommon finding on FDG PET/CT and can be the only site of relapse. From the Nuclear Medicine, Royal North Shore Hospital, Sydney, Australia. Received for publication August 9, 2018; revision accepted October 9, 2018. Conflicts of interest and sources of funding: none declared. Correspondence to: Rueben Ganeshalingam, MBBS, Nuclear Medicine, Royal North Shore Hospital, St Leonards, Sydney, New South Wales, Australia 2065. E-mail: Rueben.firstname.lastname@example.org. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.