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68Ga-DOTA-TOC PET/CT of von Hippel–Lindau Disease

Liberini, Virginia, MD*; Nicolotti, Daniele Giovanni, MD*; Maccario, Mauro, MD, AP; Finessi, Monica, MD*; Deandreis, Désirée, MD, AP*

doi: 10.1097/RLU.0000000000002395
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We present a rare case of a 42-year-old man with a long history of von Hippel–Lindau disease that was scanned with 68Ga-DOTA-TOC PET/CT for suspicion of disease relapse. 68Ga-DOTA-TOC imaging demonstrated increased DOTA-TOC uptake in pancreas tail and intramedullary and extramedullary spinal hemangioblastomas, only some of which have already been highlighted at MRI examination. This case illustrates the significant role the 68Ga-labeled somatostatin receptor analogs PET/CT in the management of the von Hippel–Lindau disease.

From the Divisions of *Nuclear Medicine, and

Endocrinology, Diabetology, and Metabolism, Department of Medical Sciences, University of Turin, Turin, Italy.

Received for publication June 27, 2018; revision accepted October 13, 2018.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Désirée Deandreis, MD, AP, Division of Nuclear Medicine, Department of Medical Sciences, University of Turin, Corso Bramante 88, 10126 Turin, Italy. E-mail:

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