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Unexpected Corpus Callosum Involvement of Diffuse Large B-Cell Lymphoma on FDG PET/CT

Kan, Ying, MD; Wang, Yu, MD; Wang, Wei, MD, PhD; Liu, Jie, MD, PhD; Yang, Jigang, MD, PhD

doi: 10.1097/RLU.0000000000002307
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Diffuse large B-cell lymphoma (DLBCL) was the most frequent subtype of lymphoid malignancy. Corpus callosum involvement of DLBCL was rarely reported. We present a case of DLBCL involving not only lymph nodes and bowels but also corpus callosum, detected by FDG PET/CT in a patient without neurological symptoms. After 4 cycles of systemic and intrathecal chemotherapy, all previously visualized abnormal activity disappeared on the follow-up FDG PET/CT.

From the Department of Nuclear Medicine, Beijing Friendship Hospital of Capital Medical University, Beijing, China.

Received for publication August 23, 2018; revision accepted August 28, 2018.

Conflicts of interest and sources of funding: J.Y. was supported by the National Natural Science Foundation of China (no. 81771860), Beijing Talents Project, and Capital's funds for Health Improvement and Research. None declared to all other authors.

Correspondence to: Jigang Yang, MD, PhD, Beijing Friendship Hospital Affiliated to Capital Medical University, 95 Yong An Road, Xi Cheng District, Beijing 100050, China. E-mail:

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