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Thyroid Metastasis From Hepatocellular Carcinoma Visualized by 18F-FDG PET/CT Imaging

Yin, Hongyan, MD*; Luo, Rongkui, MD; Xiu, Yan, MD, PhD*; Hu, Yan, MD*; Shi, Hongcheng, MD, PhD*

doi: 10.1097/RLU.0000000000002281
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Thyroid metastasis from hepatocellular carcinoma (HCC) is very rare. We present a case of a 41-year-old man with a markedly elevated serum α-fetoprotein (2,297 ng/mL) and a left neck mass 6 months after a hepatolobectomy for a primary HCC. 18F-FDG PET/CT imaging showed a focal uptake in the left thyroid lobe corresponding to a mass. The patient underwent a left hemithyroidectomy. Subsequent pathology confirmed HCC metastasis to the thyroid.

From the Departments of *Nuclear Medicine, and

Pathology, Zhongshan Hospital, Fudan University, Shanghai, China.

Received for publication February 10, 2018; revision accepted August 11, 2018.

Conflicts of interest and sources of funding: Hongyan Yin was sponsored by a Young Scholar Grant from the National Natural Science Foundation of China (81501500). None declared to all other authors.

Hongyan Yin and Rongkui Luo contributed equally to this article.

Correspondence to: Hongcheng Shi, MD, PhD, Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Rd, Shanghai, 200032, China. E-mail:

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