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Hypermetabolism Caused by Seizure Mimicking Tumor Recurrence

Wang, Jingnan, MD*†; Zhang, Yiwei, MD; Sun, Heyang, MD§; Cui, Ruixue, MD*†

doi: 10.1097/RLU.0000000000002305
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A 41-year-old man had a right frontal grade I glioma resection 17 years ago. He was tumor free since. However, 1 month ago, he presented with an uncontrollable seizure, which raised the possibility of recurrent tumor. The 18FDG PET/CT brain scan showed increased tracer uptake at the margin of the previous resected tumor, suggesting the possibility of tumor recurrence. However, on a repeat FDG PET brain scan confirmed by electroencephalography monitory as an interictal study, no elevated FDG uptake was revealed at this site. These results indicate that the elevated 18F-FDG activity on the original study was a result of seizure.

From the *Department of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital;

Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine; and

Departments of Radiology, and

§Neurology, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, China.

Received for publication August 20, 2018; revision accepted August 27, 2018.

Conflicts of interest and sources of funding: Supported by the National Natural Science Foundation of China (81771874). None declared to all authors.

Correspondence to: Ruixue Cui, MD, Department of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Wangfujing, Dongcheng District, Beijing 100730, China. E-mail: mmdhmm@126.com.

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