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Endometrioid Intraepithelial Neoplasia

An Endometrial Precancer Detected by 18F-FDG PET/CT

Chiu, Yu-Li, MD, MS*†; Wang, Jyh-Seng, MD, PhD; Peng, Nan-Jing, MD

doi: 10.1097/RLU.0000000000002294
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The report describes a 55-year-old woman with postmenopausal abnormal vaginal spotting. PET/CT revealed focal hot 18F-FDG uptake in the fundus portion of the uterine cavity, and pathology of hysteroscopic dilation and curettage showed endometrioid intraepithelial neoplasia of uterine endometrium, an endometrial precancer. This case points to the significance of 18F-FDG PET/CT in determining the dilation and curettage site for the postmenopausal women with abnormal vaginal spotting. Increased 18F-FDG activity in the region of the uterus must be investigated to determine the possibilities of primary malignancies, metastases, and benign diseases.

From the *Department of Nuclear Medicine, Kaohsiung Veterans General Hospital;

Department of Medical Imaging and Radiology, Shu-Zen Junior College of Medicine and Management;

Department of Pathology and Laboratory Medicine, Kaohsiung Veterans General Hospital, Kaohsiung; and

§School of Medicine, National Yang-Ming University, Taipei, Taiwan.

Received for publication July 13, 2018; revision accepted August 21, 2018.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Nan-Jing Peng, MD, Department of Nuclear Medicine, Kaohsiung Veterans General Hospital, No. 386, Dazhong 1st Rd., Zuoying District, Kaohsiung City 81362, Taiwan, Republic of China. E-mail:

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