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Benign Esophageal Findings on 68Ga–Prostate-Specific Membrane Antigen PET/CT Scan

Jochumsen, Mads Ryø, MD; Klingenberg, Søren, BSc(Med); Bouchelouche, Kirsten, MD, DMSc

doi: 10.1097/RLU.0000000000002295
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In 2 high-risk prostate cancer patients, PET scans revealed focally increased 68Ga–prostate-specific membrane antigen uptake in the distal esophagus. Both patients had hiatus herniation on gastroscopy, and esophageal biopsies revealed acute and chronic inflammation in both patients and a benign hyperplastic polyp in one of the patients. Recently, reports have demonstrated that inflammation can cause false-positive findings on 68Ga–prostate-specific membrane antigen PET/CT, and these cases present this phenomenon in the esophagus as well.

From the Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Aarhus, Denmark.

Received for publication August 13, 2018; revision accepted August 21, 2018.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Mads Ryø Jochumsen, MD, Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark. E-mail:

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