Primary bone lymphoma without classic nodal lesions or advanced disease may be mistaken for other osseous diseases, especially when involving a single bone site. In this patient, a series of imaging modalities including MRI, bone scan, and 18F-FDG PET/CT revealed only 1 solitary osseous lytic lesion with abnormal uptake in the third thoracic vertebra, suggesting a primary skeletal malignancy. The subsequent histopathologic examination confirmed the diagnosis of diffuse large B-cell lymphoma. After chemotherapy, he achieved an excellent clinical and metabolic response.
From the Department of Nuclear Medicine, West China Hospital of Sichuan University, Chengdu, China.
Received for publication July 13, 2018; revision accepted July 31, 2018.
Conflicts of interest and sources of funding: This study was supported by National Natural Science Foundation of China (grant 81471692). None declared to all authors.
Correspondence to: Anren Kuang, MD, Department of Nuclear Medicine, West China Hospital of Sichuan University, No. 37 Guoxue Alley, Chengdu, Sichuan 610041, China. E-mail: firstname.lastname@example.org.