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Oropharyngeal Squamous Cell Carcinoma Metastasis to Distal Skeletal Muscle on FDG PET/CT

Drew, Zachary James, BSc, MBBS

doi: 10.1097/RLU.0000000000002262
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We present a case of a tongue squamous cell carcinoma (SCC) metastasizing to distal skeletal muscle detected on FDG PET/CT imaging. A 48-year-old man with locally recurrent tongue SCC underwent a restaging FDG PET/CT to investigate neck and unilateral leg pain. The PET scan showed large, intensely FDG-avid lesions in the right scalene and left hamstring muscles, which were biopsy proven as metastatic SCC. Skeletal muscle metastases from oropharyngeal SCCs are rare; however, PET/CT has allowed increased detection of atypical metastatic sites. Such cases support the consideration of metastasis for muscular lesions in head and neck cancer patients.

From the Department of Nuclear Medicine, Royal Brisbane and Women’s Hospital, Herston, Brisbane, Queensland, Australia.

Received for publication May 6, 2018; revision accepted July 22, 2018.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Zachary Drew, BSc, MBBS, Department of Nuclear Medicine, Royal Brisbane and Women’s Hospital, Corner of Butterfield St & Bowen Bridge Rd, Herston, Brisbane 4029, Queensland, Australia. E-mail:

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