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Incidental Orbital Neuroendocrine Metastases on 111In-OctreoScan and MRI

Chen, Yin Jie, MD; Farwell, Michael D., MD

doi: 10.1097/RLU.0000000000002285
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Neuroendocrine tumors have a propensity to metastasize, but rarely to the orbits. A 69-year-old woman with history of neuroendocrine tumor of pancreatic primary underwent routine follow-up 111In-pentetreotide (OctreoScan) imaging, with 24-hour whole-body planar images showing subtle right periorbital tracer uptake that localized to extraocular muscles on subsequent SPECT/CT. Orbital MRI further defined the location of these highly suspicious orbital metastases, which were treated with external radiation, with follow-up MRI showing decreased size of the orbital metastases. Early identification and treatment of orbital metastases is critical to help preserve vision and quality of life.

From the Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

Received for publication July 29, 2018; revision accepted August 12, 2018.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Yin Jie Chen, MD, Department of Radiology, University of Pennsylvania Perelman School of Medicine, 3400 Spruce St, Philadelphia, PA 19104. E-mail: Yin.Chen@uphs.upenn.edu.

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