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Bile Collection Detected With BrIDA Scintigraphy in a Patient With Hepatocellular Carcinoma

Maccora, Daria, MD*; Di Giuda, Daniela, MD*; Ponziani, Francesca Romana, MD; Pompili, Maurizio, MD; Valenza, Venanzio, MD*

doi: 10.1097/RLU.0000000000002272
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A 47-year-old man, with a history of anabolic steroid abuse, developed hepatic adenomatosis and multifocal hepatocellular carcinoma. He underwent ultrasound and CT follow-up, showing multiple solid and fluid hepatic lesions. Consequently, hospitalization was required because of high fever (up to 39°C), weakness, and anorexia. An abdominal CT scan revealed an enlargement of one of the intrahepatic fluid collections. Biochemical and microbiological analyses of a fluid sample showed bilirubin and bile acids as well as Streptococcus cristatus and Enterobacter cloacae. Thus, the patient underwent 99mTc-trimethylbromo-iminodiacetic acid scintigraphy, demonstrating bile collection in the lesion with a flow from a bile duct.

From the *Institute of Nuclear Medicine and

Department of Internal Medicine, Gastroenterology and Hepatology, Università Cattolica del S. Cuore “A. Gemelli,” Rome, Italy.

Received for publication April 11, 2018; revision accepted July 29, 2018.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Daniela Di Giuda, MD, Institute of Nuclear Medicine, Università Cattolica del S. Cuore “A. Gemelli,” L.go A. Gemelli, 8, Rome, Italy. E-mail:

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