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A Case of Liver Injury Mimicking Metastasis After Gamma Knife Therapy for Lung Cancer

Evaluating by 18F-FDG PET/CT

Tang, Kun, MD, PhD; Zheng, Xiangwu, MD; Lin, Jie, MD; Yin, Weiwei, MD

doi: 10.1097/RLU.0000000000002283
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A 52-year-old man presented a mixed low-density lesion with high FDG uptake in hepatic segment VIII after gamma knife therapy for lung cancer, which was easily misdiagnosed as hepatic metastasis. Follow-up PET/CT assessment demonstrated that the hepatic lesion was barely observed and without FDG accumulation 5 months after radiotherapy. This case suggests that a new FDG-avid lesion at PET/CT after radiotherapy for lung cancer can be caused by radiation-induced liver injury. Knowledge of its imaging characteristics and nature course evaluated by follow-up PET/CT is critical to avoid misinterpretation of this lesion as metastases.

From the Department of PET/CT, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Received for publication July 18, 2018; revision accepted August 11, 2018.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Xiangwu Zheng, MD, The First Affiliated Hospital of Wenzhou Medical University, Xuefu North Rd, Wenzhou, Zhejiang 325000, China. E-mail:

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