A Case of Liver Injury Mimicking Metastasis After Gamma Knife Therapy for Lung Cancer Evaluating by 18F-FDG PET/CTTang, Kun, MD, PhD; Zheng, Xiangwu, MD; Lin, Jie, MD; Yin, Weiwei, MDClinical Nuclear Medicine: November 2018 - Volume 43 - Issue 11 - p 860–863 doi: 10.1097/RLU.0000000000002283 Interesting Images Abstract Author InformationAuthors Article MetricsMetrics A 52-year-old man presented a mixed low-density lesion with high FDG uptake in hepatic segment VIII after gamma knife therapy for lung cancer, which was easily misdiagnosed as hepatic metastasis. Follow-up PET/CT assessment demonstrated that the hepatic lesion was barely observed and without FDG accumulation 5 months after radiotherapy. This case suggests that a new FDG-avid lesion at PET/CT after radiotherapy for lung cancer can be caused by radiation-induced liver injury. Knowledge of its imaging characteristics and nature course evaluated by follow-up PET/CT is critical to avoid misinterpretation of this lesion as metastases. From the Department of PET/CT, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China. Received for publication July 18, 2018; revision accepted August 11, 2018. Conflicts of interest and sources of funding: none declared. Correspondence to: Xiangwu Zheng, MD, The First Affiliated Hospital of Wenzhou Medical University, Xuefu North Rd, Wenzhou, Zhejiang 325000, China. E-mail: firstname.lastname@example.org. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.