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Multiple Heterotopic Ossification of the Intestine Detected by 99mTc-MDP Bone Scan in a Patient With Primary Peritoneal Cancer

Zhang, Ruiguo, MD, PhD; Dong, Feng, MD; Meng, Zhaowei, MD, PhD; Tan, Jian, MD

doi: 10.1097/RLU.0000000000002234
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Heterotopic ossification is a rare phenomenon that refers to formation of bone outside the skeletal system. We present a 61-year-old woman who suffered from peritoneal cancer surgery 2 years ago, referred for 99mTc-MDP bone scan because of higher serum CA-125 level, which showed multiple intense tracer activities in her abdominal and pelvic region without other abnormalities. SPECT/CT revealed the activities were loaded in the intestine but not in the bone. A wait-and-see policy was adopted because of no abdominal discomfort. After 1-year follow-up, another bone scintigraphy showed the tracer uptake was significantly decreased.

From the Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, China.

Received for publication May 11, 2018; revision accepted June 29, 2018.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Jian Tan, MD, Department of Nuclear Medicine, Tianjin Medical University General Hospital, No. 154 Anshan Road, Heping District, Tianjin 300052, China. E-mail:

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