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Diffuse Liver Metastasis From Nasopharyngeal Carcinoma Found by 18F-FDG PET/CT Scans

Zhang, Xin-Yun, MD; Chen, Xiao-Yue, MD; Zhang, Guo-Qiang, MD; Luo, Quan-Yong, MD

doi: 10.1097/RLU.0000000000002211
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A 54-year-old man with a history of nasopharyngeal carcinoma was treated with TPF (docetaxel + cisplatin + 5-fluorouracil) neoadjuvant chemotherapy, presented with clinical features of acute hepatic failure. 18F-FDG PET/CT revealed diffuse hepatic radioactivity uptake without pathological radioactivity elsewhere in the body and similar to superscan by bone scan. Increased focal uptake of FDG was more commonly seen in nasopharyngeal carcinoma with metastatic involvement of the liver. This unusual liver superscan indicated that patients with nasopharyngeal carcinoma may show diffuse hepatic involvement by cancer cells and inspired our interests.

From the Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China.

Received for publication May 25, 2018; revision accepted June 8, 2018.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Quan-Yong Luo, MD, Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, 600 Yishan Road, Shanghai 200233, People’s Republic of China. E-mail: lqyn@sh163.net.

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