99mTc-Pertechnetate-SPECT/US Hybrid Imaging Enhances Diagnostic Certainty Compared With Conventional Thyroid Imaging With Scintigraphy and UltrasoundFreesmeyer, Martin, MD; Winkens, Thomas, MD; Kuehnel, Christian, MSc; Opfermann, Thomas, PhD; Seifert, Philipp, MDClinical Nuclear Medicine: October 2018 - Volume 43 - Issue 10 - p 747–748 doi: 10.1097/RLU.0000000000002241 Interesting Images Abstract Author Information Evaluation of thyroid ultrasound and 99mTc-pertechnetate scintigraphy side by side frequently produces ambiguous results regarding the correct assignment of anatomy and functionality of a nodule. We describe the usefulness of 99mTc-pertechnetate-SPECT/US-fusion imaging. A 75-year-old woman was referred for exclusion of cold nodules. After conventional diagnostics (in vitro thyroid parameters, B mode–US, planar 99mTc-pertechnetate-thyroid scintigraphy), a SPECT was performed using a conventional gamma camera. The SPECT data set was transferred to an ultrasound device (LOGIQ E9), and sensor-navigated 3D ultrasound was performed. Both data sets (SPECT/US) were fused in real time, revealing the exact functional state of multiple nodules. From the Clinic of Nuclear Medicine, Jena University Hospital, Jena, Germany. Received for publication April 6, 2018; revision accepted July 5, 2018. Conflicts of interest and sources of funding: none declared. Correspondence to: Martin Freesmeyer, MD, Clinic of Nuclear Medicine, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany. E-mail: firstname.lastname@example.org. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.