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99mTc-Pertechnetate-SPECT/US Hybrid Imaging Enhances Diagnostic Certainty Compared With Conventional Thyroid Imaging With Scintigraphy and Ultrasound

Freesmeyer, Martin, MD; Winkens, Thomas, MD; Kuehnel, Christian, MSc; Opfermann, Thomas, PhD; Seifert, Philipp, MD

doi: 10.1097/RLU.0000000000002241
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Evaluation of thyroid ultrasound and 99mTc-pertechnetate scintigraphy side by side frequently produces ambiguous results regarding the correct assignment of anatomy and functionality of a nodule. We describe the usefulness of 99mTc-pertechnetate-SPECT/US-fusion imaging. A 75-year-old woman was referred for exclusion of cold nodules. After conventional diagnostics (in vitro thyroid parameters, B mode–US, planar 99mTc-pertechnetate-thyroid scintigraphy), a SPECT was performed using a conventional gamma camera. The SPECT data set was transferred to an ultrasound device (LOGIQ E9), and sensor-navigated 3D ultrasound was performed. Both data sets (SPECT/US) were fused in real time, revealing the exact functional state of multiple nodules.

From the Clinic of Nuclear Medicine, Jena University Hospital, Jena, Germany.

Received for publication April 6, 2018; revision accepted July 5, 2018.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Martin Freesmeyer, MD, Clinic of Nuclear Medicine, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany. E-mail:

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