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18F-FDG PET/CT With Diffusely High FDG Uptake Throughout Subcutaneous Adipose Tissues

Kong, Melissa Cindy; Nadel, Helen Ruth, MD, FRCPC

doi: 10.1097/RLU.0000000000002216
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A 9-year-old girl presented with facial rash, angioedema, fevers, and night sweats. She was diagnosed with chronic active Epstein-Barr virus infection and placed on chronic steroid treatment. 18F-FDG PET/CT performed 3 weeks following presentation revealed diffuse subcutaneous soft tissue FDG activation throughout the entire body, with likely localization to white subcutaneous adipose tissue. This highly unusual appearance may have been due to the patient being treated with corticosteroids at the time of the scan.

From the Department of Radiology, British Columbia Children’s Hospital and University of British Columbia, Vancouver, BC, Canada.

Received for publication May 30, 2018; revision accepted June 13, 2018.

Conflicts of interest and sources of funding: Funding was received from BC Children’s Hospital Research Childhood Diseases Summer Studentship, UBC Faculty of Medicine Summer Student Research Program. None declared to all authors.

Correspondence to: Helen Ruth Nadel, MD, FRCPC, Department of Radiology, British Columbia Children’s Hospital, 4480 Oak St, Vancouver, BC V6H 3N1. E-mail:

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