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“Hepatic Superscan” in a Patient With Hepatosplenic Alphabeta T-cell Lymphoma

18F-FDG PET/CT Findings

Liu, Entao MD*; Wang, Siyun MD, PhD*; Lai, Peilong MD; Lian, Zhouyang MD; Wang, Shuxia MD, PhD*

doi: 10.1097/RLU.0000000000002134
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A 36-year-old woman with a 2-week history of fever and markedly elevated lactate dehydrogenase levels. Nonenhanced CT and contrast-enhanced CT showed hepatosplenomegaly, diffusely decreased attenuation of the liver, and homogeneous enhancement in the hepatic and splenic parenchyma. 18F-FDG PET/CT revealed diffuse intense heterogeneous uptake by the liver (like superscan in bone scintigraphy). A liver needle biopsy confirmed the diagnosis of hepatosplenic alphabeta T-cell lymphoma. Subsequently, she received chemotherapy. The follow-up 18F-FDG PET/CT showed decreased 18F-FDG uptake in the liver and spleen.

From the *WeiLun PET Center, Department of Nuclear Medicine, and

Departments of Haematology, and

Radiology, Guangdong General Hospital and Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, People’s Republic of China.

Received for publication February 20, 2018; revision accepted April 7, 2018.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Shuxia Wang, MD, PhD, Room 517, 5/F, Weilun Building of Guangdong General Hospital, 106 Zhonshan Er Road, Guangzhou 510080, Guangdong, People’s Republic of China. E-mail: shuxia_wangGGH@outlook.com.

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