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A Rare Case of Retroperitoneal Follicular Dendritic Cell Sarcoma Identified by 99mTc-HYNIC-TOC SPECT/CT

Li, Yi, MD*†‡§∥; Xu, Xiaoping, PhD*†‡§∥; Xu, Junyan, MD*†‡§∥; Huang, Dan, MD

doi: 10.1097/RLU.0000000000002150
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Follicular dendritic cell sarcoma is a very rare neoplasm, which is not lymphoma, but originates from a type of immune cells called follicular dendritic cells. We presented a 37-year-old woman who has suffered from obstructive jaundice, weight loss and right upper abdominal pain for 2 months. The contrast CT revealed masses located in the region of pancreatic head and lots of enlarged retroperitoneal lymph nodes, both of which were enhanced on the artery phase of CT images. Meanwhile, 99mTc-HYNIC-TOC SPECT/CT revealed high activity in the corresponding lesions. After biopsy, the masses were pathologically confirmed as retroperitoneal follicular dendritic cell sarcoma.

From the *Department of Nuclear Medicine, Fudan University Shanghai Cancer Center;

Center for Biomedical Imaging, Fudan University;

Shanghai Engineering Research Center of Molecular Imaging Probes, Fudan University;

§Department of Oncology, Shanghai Medical College, Fudan University;

Key Laboratory of Nuclear Physics and Ion-beam Application (MOE), Fudan University; and

Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China.

Received for publication March 9, 2018; revision accepted April 16, 2018.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Junyan Xu, MD Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, 270 Dong'an Road, Xuhui district, Shanghai 200032 China. E-mail:

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