Insulinomas are the most common functioning pancreatic neuroendocrine tumors and the leading cause of persistent hypoglycemia with hyperinsulinemia in adults. Glucagon-like-peptide-1 (GLP) receptor analogs are the latest agents being used in the detection of insulinomas, with initial reports suggesting high sensitivity due to universal GLP1 receptor expression on these tumors. PET/CT imaging in this patient using 68Ga DOTA-Exendin, a GLP receptor analog, proved useful for accurate localization of the culprit lesion, aiding in the definitive management of the patient.
From the Departments of *Nuclear Medicine and PET/CT,
§Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Received for publication April 3, 2018; revision accepted April 21, 2018.
Conflicts of interest and sources of funding: none declared.
Correspondence to: Bhagwant Rai Mittal, MD, DNB, Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh-160012, India. E-mail: firstname.lastname@example.org.