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Abdominal Splenosis Mimicking Peritoneal Metastasis in Prostate-Specific Membrane Antigen PET/CT, Confirmed With Selective Spleen SPECT/CT

Demirci, Emre MD*†; Has Simsek, Duygu MD; Kabasakal, Levent MD; Mülazimoğlu, Mehmet MD†§

doi: 10.1097/RLU.0000000000001878
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68Ga–prostate-specific membrane antigen (PSMA) PET/CT is a rapidly evolving diagnostic technique to image prostate cancer. In contrast to the name PSMA, various tissues show 68Ga-PSMA uptake in PET/CT imaging. We present a case of a 68-year-old man with prostate cancer who underwent Ga-PSMA PET/CT. Along with metastatic lymph nodes, multiple nodular lesions within the peritoneal spaces of all 4 quadrants of the abdomen showed high PSMA expression. Because of a history of splenic rupture, a 99mTc-labeled heat-denatured erythrocyte scintigraphy and SPECT were performed. Peritoneal lesions showed high uptake, confirming widespread peritoneal splenosis.

From the *Department of Nuclear Medicine, Yeditepe University School of Medicine; †Department of Nuclear Medicine, Sisli Etfal Training and Research Hospital, University of Health Sciences; ‡Department of Nuclear Medicine, Cerrahpasa Faculty of Medicine, Istanbul University; and §Department of Nuclear Medicine, Okmeydani Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Received for publication September 20, 2017; revision accepted September 20, 2017.

Conflicts of interest and sources of funding: none declared.

This study was performed at the Department of Nuclear Medicine, Şişli Etfal Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Correspondence to: Emre Demirci, MD, Department of Nuclear Medicine, Yeditepe University School of Medicine, 168 Koşuyolu Cad. 34718 Kadiköy, İstanbul. E-mail: emredemirci@gmail.com.

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