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False-Positive Pancreatic Uptake Detected on 68Ga-PSMA PET/CT

A Priority Changing Incidental Finding While Assessing the Need for a Prostate Biopsy

Demirkol, Mehmet Onur, MD*†; Kiremit, Murat Can, MD; Acar, Omer, MD§; Sag, Alan Alper, MD; Kapran, Yersu, MD

doi: 10.1097/RLU.0000000000001834
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A 72-year-old man underwent 68Ga-PSMA PET/CT because of an elevated prostate-specific antigen level despite prior prostatectomy. Besides low-intensity prostatic PSMA reactivities, a faintly PSMA-positive lesion in the pancreatic corpus drew attention, which seemed suggestive of a primary pancreatic cancer on the subsequent MRI and therefore had to be excised. The final diagnosis was pT3 low-grade neuroendocrine tumor. PSMA-positive incidentalomas, detected on 68Ga-PSMA PET/CT, can reveal more clinically significant extraprostatic disorders.

From the *Department of Nuclear Medicine and Molecular Imaging, School of Medicine, Koc University; †Department of Nuclear Medicine and Molecular Imaging, VKF American Hospital; ‡Department of Urology, Koc University Hospital; and Departments of §Urology, ∥Radiology, and ¶Pathology, School of Medicine, Koc University, Istanbul, Turkey.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Murat Can Kiremit, MD, Department of Urology, Koc University Hospital, Davutpaşa Caddesi No. 4, 34010 Topkapi, İstanbul, Turkey. E-mail: mckiremit@gmail.com.

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