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Adefovir-Induced Hypophosphatemic Osteomalacia Mimicking Bone Metastases From Primary Hepatocarcinoma

Wei, Wei-Jun, MD; Sun, Zhen-Kui, MD; Shen, Chen-Tian, MD; Qiu, Zhong-Ling, MD; Luo, Quan-Yong, MD

doi: 10.1097/RLU.0000000000001756
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Adefovir-induced hypophosphatemic osteomalacia in the context of hepatocarcinoma is rare and needs to be differentiated from metastatic hepatocarcinoma. We here report a case of severe osteomalacia whose focal uptakes of radiotracer on the 99mTc-MDP SPECT/CT images mimicked that of metastatic hepatocarcinoma.

From the Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China.

Received for publication March 27, 2017; revision accepted June 3, 2017.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Quan-Yong Luo, MD, Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, 600# Yishan Road, 200233, Shanghai, China. E-mail: lqyn@sh163.net.

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