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Lymphoma and Lactic Acidosis

McKay, John W. MD; Delbeke, Dominique MD, PhD; Sandler, Martin P. MD

doi: 10.1097/RLU.0000000000001596
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A 39-year-old man presented with new onset of sinus congestion, shortness of breath, and diaphoresis. His laboratory tests were notable for hypercalcemia and lactic acidosis. A CT scan of the head demonstrated mild paranasal disease. CT scan of the chest, abdomen, and pelvis demonstrated omental caking with lymphadenopathy and a thickened loop of bowel in the left upper quadrant suggestive of lymphoma. All abdominal lesions seen in the CT were intensely 18F-FDG avid with diffuse uptake in the bone marrow. There was markedly decreased 18F-FDG uptake in both the brain and liver. Histopathology was positive for Burkitt lymphoma.

From the Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN.

Received for publication October 11, 2016; revision accepted January 9, 2017.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Dominique Delbeke, MD, PhD, Department of Radiology and Radiological Sciences, 1611 21st Ave S, CCC-1121 Medical Center North, Vanderbilt University Medical Center, Nashville, TN 37232. E-mail:

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