Interesting ImagesEvaluation of a Large Renal Mass Using 99mTc-MIBI SPECT/CT in a Patient With Chronic Kidney DiseaseRowe, Steven P. MD, PhD*; Gorin, Michael A. MD†; Javadi, Mehrbod S. MD*; Allaf, Mohamad E. MD†Author Information From the *The Russell H. Morgan Department of Radiology and Radiological Science, and †The James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins University School of Medicine, Baltimore, MD. Received for publication June 13, 2016; revision accepted November 28, 2016. Conflicts of interest and sources of funding: none declared. Correspondence to: Steven P. Rowe, MD, PhD, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine 601 N Caroline St, Baltimore, MD 21287. E-mail: email@example.com. Clinical Nuclear Medicine: March 2017 - Volume 42 - Issue 3 - p e166-e167 doi: 10.1097/RLU.0000000000001533 Buy Metrics Abstract The differentiation of benign and indolent renal masses from aggressive tumor histologies cannot be reliably performed by CT or MRI. Additionally, renal mass biopsy risks complications and has a nondiagnostic rate of 10% to 20%. 99mTc-MIBI SPECT/CT has been shown to allow for the accurate differentiation of benign renal oncocytomas and hybrid oncocytic/chormophobe tumors from other more aggressive renal tumor types. We present the case of an 84-year-old man with chronic kidney disease and an 11.2-cm renal mass. Results of his 99mTc-MIBI SPECT/CT allowed avoidance of a radical nephrectomy. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.