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18F-FDG PET/CT in Metastatic Pilomatrix Carcinoma

Vadrucci, Manuela, MD; Gilardi, Laura, MD; Crivelli, Filippo, MD; Baroli, Alberto, MD; Lomuscio, Giuseppe, MD

doi: 10.1097/RLU.0000000000001405
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We describe the FDG PET/CT findings in an exceedingly rare case of metastatic pilomatrix carcinoma (PC). A 76-year-old man, who underwent incisional biopsy of a soft-tissue mass in the frontal scalp that revealed PC, was referred for an 18F-FDG PET/CT scan for staging purposes. PET/CT showed areas of increased radiotracer uptake corresponding to frontal mass and unsuspected lung lesions, which were later confirmed as metastases from PC at histological analysis. Clinical condition deteriorated rapidly, and the patient died 3 months after the initial diagnosis.

From the *Department of Health Sciences, University of Milan, Milan; †Department of Nuclear Medicine, ASST Valle Olona Busto Arsizio Hospital, Varese; ‡Department of Nuclear Medicine, European Institute of Oncology, Milan; and §Department of Pathology, ASST Valle Olona Busto Arsizio Hospital, Varese, Italy.

Received for publication March 2, 2016; revision accepted August 26, 2016.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Manuela Vadrucci, MD, Department of Nuclear Medicine, Department of Health Sciences, University of Milan, Milan, Italy. E-mail:

Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.