Interesting ImagesFDG PET/CT in Sarcomatoid Carcinoma of the Gallbladder With Chondroid DifferentiationDong, Aisheng MD; Dong, Hui MD; Jing, Wei MD; Zuo, Changjing MDAuthor Information From the *Department of Nuclear Medicine, Changhai Hospital; †Department of Pathology, Eastern Hepatobiliary Surgery Hospital; and ‡Department of General Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China. Received for publication December 8, 2015; revision accepted December 20, 2015. Conflicts of interest and sources of funding: none declared. Aisheng Dong and Hui Dong contributed equally to the article. Correspondence to: Changjing Zuo, MD, Department of Nuclear Medicine, Changhai Hospital, Second Military Medical University, 168 Changhai Rd, Yangpu District, Shanghai 200433, China. E-mail: [email protected]; Wei Jing, MD, Department of General Surgery, Changhai Hospital, Second Military Medical University, 168 Changhai Rd, Yangpu District, Shanghai 200433, China. E-mail: [email protected]. Clinical Nuclear Medicine: August 2016 - Volume 41 - Issue 8 - p 638-640 doi: 10.1097/RLU.0000000000001160 Buy Metrics Abstract Sarcomatoid carcinoma of the gallbladder, composed of epithelial and sarcomatous components, is a rare malignant tumor with a poor prognosis. A 61-year-old man was admitted because of abdominal distention for 2 weeks. Enhanced CT showed a large gallbladder tumor with central necrosis. The tumor measuring 18 cm in maximum diameter showed intense peripheral FDG uptake with SUVmax of 15.4. The specimen of the resected tumor revealed tubular adenocarcinoma and sarcomatoid tissue with chondroid differentiation. Immunohistochemical staining showed the sarcomatoid tissue was positive for EMA, CD10, and VIM, with proliferation index of 80%. These pathologic findings were consistent with sarcomatoid carcinoma. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.