Two patients were referred to our emergency department with myalgia, fever, general malaise, eosinophilia, and elevated serum levels of creatine kinase and troponin T. 18F-FDG PET/CT scan was performed showing a diffuse and homogenous moderately elevated glucose uptake in all muscle groups. Trichinella spiralis infection was confirmed by a muscle biopsy and detection of trichinella antibodies. The muscle biopsy was taken in the left quadriceps because of equal involvement of the skeletal muscles. The differential diagnosis of diffuse 18F-FDG muscle uptake should include trichinella infection, in particular, in the presence of infectious symptoms, eosinophilia, and biochemical signs of muscle damage.
From the Departments of *Nuclear Medicine, †Pathology, and ‡Internal Medicine, University Hospitals Leuven, Leuven, Belgium.
Received for publication January 21, 2015; revision accepted June 9, 2015.
Christophe M. Deroose, PhD, MD, and Donatienne Van Weehaeghe contributed equally to this study.
Conflicts of interest and sources of funding: none declared.
Correspondence to: Christophe M. Deroose, PhD, MD, Department of Nuclear Medicine, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium. E-mail: firstname.lastname@example.org.