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Unusual Bone Superscan, MIBG Superscan, and 68Ga DOTATATE PET/CT in Metastatic Pheochromocytoma

Tan, Teik Hin, MD*; Wong, Teck Huat, MD; Hassan, Siti Zarina Amir, MD; Lee, Boon Nang, MD*

doi: 10.1097/RLU.0000000000000920
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A 17-year-old adolescent boy with biochemically raised 2-hour urinary metanephrine and normetanephrine as well as CT findings of retroperitoneal soft tissue mass and bony metastases was referred for further assessment. Apart from 68Ga DOTATATE PET/CT evaluation, pretargeted systemic radionuclide therapy assessment with 131I-MIBG scintigraphy showed unusual phenomenon of MIBG superscan. Postsurgically, restaging 99mTc-MDP bone scintigraphy showed typical bone superscan features. The MIBG superscan was better delineated on post–131I-MIBG therapy images.

From the *Department of Nuclear Medicine, National Cancer Institute, Putrajaya; and †Department of Nuclear Medicine, Kuala Lumpur Hospital, Kuala Lumpur, Malaysia.

Received for publication July 29, 2014; revision accepted May 22, 2015.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Teik Hin Tan, MD, Department of Nuclear Medicine, National Cancer Institute, No 4, Jalan P7, Presint 7, 62550, Putrajaya, Malaysia. E-mail:

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