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99mTc Disphosphonate Uptake Due to Splenosis

Incidental Finding 60 Years After Splenectomy

Baldari, Giorgio MD*; Sindoni, Alessandro MD; Belletti, Alice MSc*; Baldari, Sergio MD; Ruffini, Livia MD*

doi: 10.1097/RLU.0000000000000752
Interesting Images

A 72-year-old man was referred for a triphasic bone scintigraphy to evaluate painful prosthetic implant of the knee. In all the study phases, images showed abnormal uptake close to the tibial portion of the implant. Interestingly, later whole-body images revealed high radiopharmaceutical accumulation in the left hypochondrium. Subsequent radiolabeled leukocyte scintigraphy confirmed radiotracer accumulation in the same localizations. As an important background the patient underwent splenectomy owing to Banti syndrome 60 years earlier. A 99mTc-labeled heat-damaged red blood cell scintigraphy was then performed, which confirmed radiopharmaceutical accumulation in the left hypochondrium being consistent with splenosis.

From the *Nuclear Medicine Unit, University Hospital of Parma, Italy; and †Department of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy.

Received for publication September 14, 2014; revision accepted January 9, 2015.

Conflicts of interest and sources of funding: none declared.

Reprints: Giorgio Baldari, MD, Nuclear Medicine Unit, University Hospital of Parma, Parma, Italy. E-mail:

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