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111In WBC SPECT/CT Detection of a Radiographically Occult Solitary Infected Renal Cyst in Polycystic Kidney Disease

Guy, Matthew S. DO; Kardan, Arash MD

doi: 10.1097/RLU.0000000000000771
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Renal cyst infection—pyocystis—is a potentially life-threatening complication of autosomal-dominant polycystic kidney disease. Differentiation of pyocystis from pyelonephritis is important for antibiotic management. A 56-year-old woman with autosomal-dominant polycystic kidney disease and recurrent urinary tract infections was admitted to the hospital with suspicion of pyelonephritis. CT and static planar 111In-labeled WBC examinations failed to show a specific focus of infection. Abdominal imaging with 111In-labeled WBC SPECT/CT revealed abnormal leukocyte accumulation within a solitary right renal cyst. Precise SPECT/CT localization of the infected renal cyst is illustrated along with comparative CT images.

From the Kettering Medical Center, Kettering, OH.

Received for publication November 6, 2014; revision accepted January 22, 2015.

Conflicts of interest and sources of funding: none declared.

Reprints: Matthew S. Guy, DO, Department of Radiology, Kettering Medical Center, 3535 Southern Blvd, Kettering, OH 45429. E-mail: msguy55@gmail.com.

Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.