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Dramatic Change in 18F-FDG Uptake in a Sarcoidosis Case Showing Spontaneous Recovery

Ito, Kimiteru MD*; Miyata, Yoko MD; Minamimoto, Ryogo MD; Kubota, Kazuo MD

doi: 10.1097/RLU.0b013e31828e973b
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A 47-year-old man with treatment-naive sarcoidosis underwent 18F-FDG PET/CT. The image revealed clearly abnormal uptakes in his lymph nodes, muscles, and lungs, consistent with lesions of sarcoidosis. The patient had no symptoms and was under observation without treatment for sarcoidosis. At a 2-year follow-up, he underwent another 18F-FDG PET/CT scan, which revealed that several lesions with abnormal FDG uptake had significantly decreased, and some lesions had completely disappeared. Because sarcoidosis frequently shows spontaneous recovery, FDG uptake may show spontaneously dynamic changes in the associated lesions.

From the *Department of Radiology, National Center of Neurology and Psychiatry; and †Department of Radiology, National Center for Global Health and Medicine, Tokyo, Japan.

Received for publication January 15, 2013; revision accepted February 12, 2013.

Conflicts of interest and sources of funding: none declared.

Reprints: Kimiteru Ito, MD, Department of Radiology, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi-cho, Kodaira, Tokyo, Japan. E-mail:

© 2014 by Lippincott Williams & Wilkins