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Bilateral Lung 99mTc-MDP Uptake on the Bone Scintigraphy in the Myelodysplastic Syndromes (MDS)

Mogharrabi, Mehdi MD*; Javadi, Hamid MD; Assadi, Majid MD

doi: 10.1097/RLU.0b013e3182868266
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We report a case of myelodysplastic syndrome (MDS) with unusual abnormal 99mTc-MDP activity throughout both lungs on whole-body bone scan. To explain the pancytopenia, bone marrow examination was carried out which showed hypocellularity in addition to large abnormal megakaryocytes indicating myelodysplastic changes. His whole-body bone scan showed increased 99mTc-MDP activity in both lungs, kidneys, and also along the proximal two thirds of the femora. It was concluded that lung uptake in addition to skeletal uptake on scintigraphic bone scanning should be kept in mind in patients with MDS.

From the *Department of Nuclear Medicine, 5th Azar Hospital and †Golestan Research Center of Gastroenterology and Hepatology (GRCGH), Golestan University of Medical Sciences (GUOMS), Gorgan; and ‡The Persian Gulf Nuclear Medicine Research Center, Bushehr University of Medical Sciences, Bushehr, Iran.

Received for publication July 16, 2012; and revision accepted December 29, 2012.

Reprints: Majid Assadi, MD, The Persian Gulf Nuclear Medicine Research Center, The Persian Gulf Biomedical Sciences Institute, Boostan 19 Alley, Sangi Street, Bushehr, Iran. E-mail:

Conflicts of interest and sources of funding: none declared.

© 2013 by Lippincott Williams & Wilkins